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|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|NC318||NC-318|NC 318|Anti-S15 mAb NC318||NC318 is a monoclonal antibody that binds to sialic acid binding Ig-like lectin 15 (Siglec-15) expressed on tumor-associated macrophages, which potentially disrupts T-cell response inhibition, and may interfere with angiogenesis and tumor cell metastasis (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT03665285||Phase Ib/II||NC318||A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors||Recruiting|