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Therapy Name MRG002
Synonyms
Therapy Description

MRG002 consists of a humanized anti-ERBB2 (HER2) IgG1 antibody in conjugation with a cytotoxic agent monomethyl auristatin E (MMAE), which may have antitumor activity against ERBB2 (HER2)-positive tumors (Journal of Clinical Oncology 38, no. 15_suppl, Abstract TPS1101).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
MRG002 MRG 002|MRG-002 HER2 (ERBB2) Antibody 72 MRG002 consists of a humanized anti-ERBB2 (HER2) IgG1 antibody in conjugation with a cytotoxic agent monomethyl auristatin E (MMAE), which may have antitumor activity against ERBB2 (HER2)-positive tumors (Journal of Clinical Oncology 38, no. 15_suppl, Abstract TPS1101).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04492488 Phase Ib/II MRG002 A Study of MRG002 in Patients With HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer Unknown status USA 0


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