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Molecular Profile | ERBB4 G936R |
Therapy | Erlotinib |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
ERBB4 G936R | Advanced Solid Tumor | sensitive | Erlotinib | Preclinical - Cell culture | Actionable | In a preclinical study, transformed cells expressing ERBB4 G936R demonstrated sensitivity to Tarceva (erlotinib) similar to wild-type Erbb4 in culture, resulting in decreased cell viability (PMID: 33323455). | 33323455 |
PubMed Id | Reference Title | Details |
---|---|---|
(33323455) | Identification of Predictive ERBB Mutations by Leveraging Publicly Available Cell Line Databases. | Full reference... |