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Therapy Name | ION537 |
Synonyms | |
Therapy Description |
ION537 is a YAP1 antisense oligonucleotide (ASO), which potentially reduces YAP1 expression resulting in reduced cell proliferation and inhibition of tumor growth (Cancer Res 2021;81(13_Suppl):Abstract nr ND11). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
ION537 | ION 537|ION-537 | YAP Inhibitor 3 | ION537 is a YAP1 antisense oligonucleotide (ASO), which potentially reduces YAP1 expression resulting in reduced cell proliferation and inhibition of tumor growth (Cancer Res 2021;81(13_Suppl):Abstract nr ND11). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04659096 | Phase I | ION537 | A Study of ION537 in Patients With Molecularly Selected Advanced Solid Tumors | Completed | USA | 0 |