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|Therapy Name||Anti-GPC3-scFvGC33-CAR autologous T Lymphocytes|
|Drug Name||Trade Name||Synonyms||Drug Classes||Drug Description|
|Anti-GPC3-scFvGC33-CAR autologous T Lymphocytes||GAP T cells||Anti-GPC3-scFvGC33-CAR autologous T Lymphocytes are autologous T-cells that have been engineered to express a chimeric antigen receptor (CAR) based on an antibody (GC33) that targets GPC3, which may induce lysis of GPC3-expressing tumor cells (NCI Drug Dictionary).|
|Molecular Profile||Indication/Tumor Type||Response Type||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|
|NCT02932956||Phase I||Cyclophosphamide + Fludarabine Anti-GPC3-scFvGC33-CAR autologous T Lymphocytes||Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors (GAP) (GAP)||Recruiting|