Therapy Detail

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Therapy Name TK-8001
Synonyms
Therapy Description

TK-8001 is a T-cell receptor-based therapy that targets melanoma-associated antigen 1 (MAGE-A1) expressed on tumor cells, potentially resulting in antitumor activity (Journal for ImmunoTherapy of Cancer 2021;9).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
TK-8001 TK 8001|TK8001 TK-8001 is a T-cell receptor-based therapy that targets melanoma-associated antigen 1 (MAGE-A1) expressed on tumor cells, potentially resulting in antitumor activity (Journal for ImmunoTherapy of Cancer 2021;9).

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05430555 Phase Ib/II TK-8001 A Phase 1/2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/Metastatic MAGE-A1+ Solid Tumors (IMAG1NE) Terminated NLD | GBR | ESP | DEU | BEL 0


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