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Therapy Name | TdCyd |
Synonyms | |
Therapy Description |
TdCyd is a DNA demethylating agent shown to diminish the levels of DNA methyltransferase 1 (DNMT1), which may result in tumor growth inhibition (PMID: 24908436). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
TdCyd | 4'-thio-2'-deoxycytidine|4-Thio-2-deoxycytidine | DNMT1 inhibitor 4 | TdCyd is a DNA demethylating agent shown to diminish the levels of DNA methyltransferase 1 (DNMT1), which may result in tumor growth inhibition (PMID: 24908436). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02423057 | Phase I | TdCyd | Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors | Suspended | USA | 0 |