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Therapy Name | COH29 |
Synonyms | |
Therapy Description |
COH29 inhibits human ribonucleotide reductase (RNR), which may lead to inhibition of DNA synthesis and repair, resulting in tumor growth inhibition (PMID: 25814515). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
COH29 | COH 29|COH-29 | COH29 inhibits human ribonucleotide reductase (RNR), which may lead to inhibition of DNA synthesis and repair, resulting in tumor growth inhibition (PMID: 25814515). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02112565 | Phase I | COH29 | RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists | Active, not recruiting | USA | 0 |