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Molecular Profile | FGFR2 V564I |
Therapy | Pemigatinib |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 V564I | Advanced Solid Tumor | predicted - sensitive | Pemigatinib | Preclinical - Biochemical | Actionable | In a preclinical study, Pemazyre (pemigatinib) treatment inhibited activity of FGFR2 V564I in a kinase assay (PMID: 36698015). | 36698015 |
PubMed Id | Reference Title | Details |
---|---|---|
(36698015) | Characterization of the cholangiocarcinoma drug pemigatinib against FGFR gatekeeper mutants. | Full reference... |