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Therapy Name OMTX705
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
OMTX705 OMTX 705|OMTX-705 OMTX705 is an antibody drug conjugate that targets fibroblast-activating protein alpha, and may resulting in inhibition of tumor growth, T cell infiltration and increased killing of tumor cells (PMID: 32161121).

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
Unknown unknown ovarian cancer not applicable OMTX705 Preclinical - Pdx Actionable In a preclinical study, OMTX705 treatment inhibited tumor growth in a patient-derived xenograft (PDX) model of ovarian cancer (PMID: 32161121). 32161121
Unknown unknown lung non-small cell carcinoma not applicable OMTX705 Preclinical - Pdx Actionable In a preclinical study, OMTX705 treatment inhibited tumor growth in a patient-derived xenograft (PDX) model of non-small cell lung cancer (PMID: 32161121). 32161121
Unknown unknown pancreatic cancer not applicable OMTX705 Preclinical - Pdx Actionable In a preclinical study, OMTX705 treatment induced apoptosis, reduced proliferation, and led to tumor growth inhibition and regression in a patient-derived xenograft (PDX) model of pancreatic cancer (PMID: 32161121). 32161121
Unknown unknown triple-receptor negative breast cancer not applicable OMTX705 Preclinical - Pdx Actionable In a preclinical study, OMTX705 treatment inhibited tumor growth in a patient-derived xenograft (PDX) model of triple-negative breast cancer (PMID: 32161121). 32161121

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries


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