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Therapy Name | BNT153 |
Synonyms | |
Therapy Description |
BNT153 consists of an mRNA for IL-2 contained within a lipid nanoparticle, which activates IL2Rb-dependent signaling, potentially resulting in increased antitumor response and tumor cell killing (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
BNT153 | BNT-153|BNT 153 | BNT153 consists of an mRNA for IL-2 contained within a lipid nanoparticle, which activates IL2Rb-dependent signaling, potentially resulting in increased antitumor response and tumor cell killing (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04710043 | Phase I | BNT152 BNT153 | Dose Escalation Trial of BNT152+153 in Patients With Cancer | Recruiting | USA | 1 |