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|Profile Name||RET R886W|
|Gene Variant Detail|
|Relevant Treatment Approaches|
|Molecular Profile||Indication/Tumor Type||Response Type||Relevant Treatment Approaches||Therapy Name||Approval Status||Evidence Type||Efficacy Evidence||References|
|RET R886W||Advanced Solid Tumor||sensitive||Sorafenib||Preclinical - Cell culture||Actionable||In a preclinical study, transformed cells expressing RET R886W were sensitive to treatment with Nexavar (sorafenib) in culture, demonstrating reduced cell proliferation (PMID: 21551259).||21551259|
|Clinical Trial||Phase||Therapies||Title||Recruitment Status|