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Therapy Name | PM060184 |
Synonyms | |
Therapy Description |
Plocabulin (PM060184) is an anti-tubulin, which also binds to the minor groove of DNA, which may cause delayed progression through S-phase, premature cell cycle arrest, and cell death (PMID: 24486569, PMID: 32711367). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
PM060184 | Plocabulin | PM-060184|PM 060184 | Plocabulin (PM060184) is an anti-tubulin, which also binds to the minor groove of DNA, which may cause delayed progression through S-phase, premature cell cycle arrest, and cell death (PMID: 24486569, PMID: 32711367). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT01299636 | Phase I | PM060184 | Study of PM060184 in Patients With Advanced Solid Tumors | Completed | USA | 0 |