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Therapy Name | CT-0508 |
Synonyms | |
Therapy Description |
CT-0508 consists of adenovirus-transduced macrophages expressing an anti-Erbb2 (Her2) chimeric antigen receptor (CAR), which may activate the tumor microenvironment and stimulate anti-tumor immune response (Cancer Immunol Res 2020;8(3 Suppl):Abstract nr B65). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
CT-0508 | CT 0508|CT0508|Ad5f35-transduced anti-HER2 CAR-M | CT-0508 consists of adenovirus-transduced macrophages expressing an anti-Erbb2 (Her2) chimeric antigen receptor (CAR), which may activate the tumor microenvironment and stimulate anti-tumor immune response (Cancer Immunol Res 2020;8(3 Suppl):Abstract nr B65). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04660929 | Phase I | CT-0508 | CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors | Active, not recruiting | USA | 0 |