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Therapy Name | PF-07209960 |
Synonyms | |
Therapy Description |
PF-07209960 is a fusion protein comprised of a PDCD PD-1 targeting region that binds to and inhibits PDCD1 (PD-1) on tumor cells, fused to a mutein of the cytokine IL-15 that binds to and activates the IL-15 receptor, potentially resulting in activation of anti-tumor immune response and increased tumor cell death (NCI Thesaurus). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
PF-07209960 | PF 07209960|PF07209960 | PF-07209960 is a fusion protein comprised of a PDCD PD-1 targeting region that binds to and inhibits PDCD1 (PD-1) on tumor cells, fused to a mutein of the cytokine IL-15 that binds to and activates the IL-15 receptor, potentially resulting in activation of anti-tumor immune response and increased tumor cell death (NCI Thesaurus). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT04628780 | Phase I | PF-07209960 | Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors | Terminated | USA | 0 |