Therapy Detail

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Therapy Name Fenretinide
Synonyms
Therapy Description

Fenretinide is a retinol analog that binds and activates retinoic acid receptors, potentially resulting in increased tumor cell apoptosis (PMID: 32497314).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Fenretinide 4-HPR|McN-R-1967|fenretinimide Fenretinide is a retinol analog that binds and activates retinoic acid receptors, potentially resulting in increased tumor cell apoptosis (PMID: 32497314).

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02163356 Phase I Vincristine Sulfate Fenretinide Ketoconazole Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant Neuroblastoma Terminated USA 0
NCT04234048 Phase I Fenretinide Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma Recruiting USA 0
NCT02075177 Phase I Ketoconazole Fenretinide Expanded Access Study of Fenretinide Lym-X-Sorb Plus Ketoconazole in Neuroblastoma No longer available USA 0
NCT01535157 Phase Ib/II Ketoconazole Fenretinide Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer Terminated USA 0
NCT01553071 Phase I Safingol Fenretinide Phase I Trial of IV Fenretinide (4-HPR) Plus IV Safingol for Patients With Relapsed Malignancies Terminated USA 0
NCT02495415 Phase II Fenretinide Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas Unknown status USA 0
NCT01187810 Phase I Fenretinide Cytarabine Methotrexate Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL Terminated USA 0


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