Therapy Detail

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Therapy Name APX3330
Synonyms
Therapy Description

APX3330 (E3330) inhibits redox factor 1 (REF1, APEX1), potentially resulting in decreased tumor angiogenesis and increased apoptosis and reduced viability, and proliferation of tumor cells (PMID: 19097035, PMID: 28446640, PMID: 31413178).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
APX3330 APX-3330|APX 3330|E3330|E 3330 APX3330 (E3330) inhibits redox factor 1 (REF1, APEX1), potentially resulting in decreased tumor angiogenesis and increased apoptosis and reduced viability, and proliferation of tumor cells (PMID: 19097035, PMID: 28446640, PMID: 31413178).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03375086 Phase I APX3330 A Study of APX3330 in Patients With Advanced Solid Tumors (APX3330) Completed USA 0


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