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Therapy Name GBR1302
Synonyms
Therapy Description

GBR1302 is a bispecific antibody that targets both ERBB2 (HER2) and CD3, which may have anti-tumor activity against ERBB2 (HER2)-positive tumors (European Journal of Cancer, Vol. 50, 48 (abst nr. 139), PMID: 32054397).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
GBR1302 GBR 1302|GBR-1302 CD3 Antibody 92 HER2 (ERBB2) Antibody 72 GBR1302 is a bispecific antibody that targets both ERBB2 (HER2) and CD3, which may have anti-tumor activity against ERBB2 (HER2)-positive tumors (European Journal of Cancer, Vol. 50, 48 (abst nr. 139), PMID: 32054397).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02829372 Phase I GBR1302 Phase 1 Study of Single Agent GBR 1302 in Subjects With HER2 Positive Cancers (GBR 1302-101) Terminated USA | DEU 0
NCT03983395 Phase Ib/II GBR1302 Study of GBR 1302 (CD3 Bispecific Ab) in HER2-positive Metastatic Breast Cancer Terminated USA 0


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