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Therapy Name | CEP-37440 |
Synonyms | |
Therapy Description |
CEP-37440 is a dual kinase inhibitor, which binds to and inhibits ALK and FAK, resulting in decreased downstream signaling and reduced tumor growth (PMID: 25322323, PMID: 27527804). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
CEP-37440 | ALK Inhibitor 32 FAK inhibitor 15 | CEP-37440 is a dual kinase inhibitor, which binds to and inhibits ALK and FAK, resulting in decreased downstream signaling and reduced tumor growth (PMID: 25322323, PMID: 27527804). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT01922752 | Phase I | CEP-37440 | To Determine the Maximum Tolerated Dose of Oral CEP-37440 in Patients With Advanced or Metastatic Solid Tumors | Completed | USA | 0 |