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Therapy Name Cobolimab
Synonyms
Therapy Description

Cobolimab (TSR-022) is a monoclonal antibody that targets T-cell immunoglobulin and mucin domain-3 protein (TIM-3, HAVCR2), potentially resulting in enhanced anti-tumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2504).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Cobolimab TSR-022 Immune Checkpoint Inhibitor 148 TIM-3 Antibody 8 Cobolimab (TSR-022) is a monoclonal antibody that targets T-cell immunoglobulin and mucin domain-3 protein (TIM-3, HAVCR2), potentially resulting in enhanced anti-tumor immune response (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 2504).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06238635 Phase II Cobolimab + Dostarlimab-gxly Cobolimab Dostarlimab and Cobolimab in Advanced Cervical Cancer Recruiting USA 0
NCT06322693 Phase I Cobolimab + Docetaxel Cisplatin + Cobolimab + Dostarlimab-gxly + Pemetrexed Disodium Cobolimab + Docetaxel + Dostarlimab-gxly Cobolimab + Dostarlimab-gxly Cobolimab Cobolimab + Dostarlimab-gxly + TSR-033 Cobolimab + Nivolumab A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER) Recruiting USA | ESP 1
NCT02817633 Phase I Cobolimab Cobolimab + unspecified PD-1 antibody A Phase 1 Study of TSR-022, an Anti-TIM-3 Monoclonal Antibody, in Patients With Advanced Solid Tumors Recruiting USA | ESP 1


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