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Therapy Name DB-1311
Synonyms
Therapy Description

DB-1311 is an antibody-drug conjugate (ADC) comprising a B7-H3 (CD276) antibody conjugated to the topoisomerase inhibitor P1021, which potentially decreases growth of B7-H3 (CD276)-expressing tumors (Cancer Res (2023) 83 (7_Supplement): 2967).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
DB-1311 DB 1311|DB1311 CD276 Antibody 12 DB-1311 is an antibody-drug conjugate (ADC) comprising a B7-H3 (CD276) antibody conjugated to the topoisomerase inhibitor P1021, which potentially decreases growth of B7-H3 (CD276)-expressing tumors (Cancer Res (2023) 83 (7_Supplement): 2967).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05914116 Phase Ib/II DB-1311 A Study of DB-1311 in Advanced/Metastatic Solid Tumors Recruiting USA | AUS 0


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