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Drug Name Trade Name Synonyms Drug Classes Drug Description
Autologous TAPA-pulsed dendritic cell vaccine Autologous TAPA-pulsed dendritic cell vaccine is a vaccine comprised of autologous dendritic cells that have been pulsed with tumor-associated peptide antigens, which may initiate an immune response against tumor cells expressing the specific tumor associated peptide antigens (NCI Drug Dictionary).
Cyclophosphamide Cytoxan CPM Chemotherapy - Alkylating 14 Cytoxan (cyclophosphamide) is an alkylating agent, which inhibits DNA replication (NCI Drug Dictionary). Cytoxan (cyclophosphamide) is FDA approved in multiple hematological malignancies, breast cancer, neuroblastoma, ovarian cancer, and retinoblastoma (NCI Drug Dictionary).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status
NCT02224599 Phase Ib/II Autologous TAPA-pulsed dendritic cell vaccine + Cyclophosphamide Cyclophosphamide, TAPA-Pulsed Dendritic Cell Therapy and Imiquimod in Progressive and/or Refractory Solid Malignancies Terminated


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