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Therapy Name | PBF 999 |
Synonyms | |
Therapy Description |
PBF 999 inhibits both adenosine A2A receptor (A2AR) and phosphodiesterase 10A (PDE-10A), which potentially leads to activation of immune response and inhibition of tumor cell growth (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
PBF 999 | PBF-999|PBF999 | Adenosine Targeting 23 | PBF 999 inhibits both adenosine A2A receptor (A2AR) and phosphodiesterase 10A (PDE-10A), which potentially leads to activation of immune response and inhibition of tumor cell growth (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT03786484 | Phase I | PBF 999 | Study of PBF-999 in Solid Tumour Advanced Cancer | Completed | ESP | 0 |