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Molecular Profile | FGFR2 A389T |
Therapy | AZD4547 |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
FGFR2 A389T | Advanced Solid Tumor | predicted - sensitive | AZD4547 | Preclinical - Cell culture | Actionable | In a preclinical study, cells expressing FGFR2 A389T were sensitive to treatment with AZD4547 in culture, demonstrating reduced cell viability (PMID: 34272467). | 34272467 |
PubMed Id | Reference Title | Details |
---|---|---|
(34272467) | Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer. | Full reference... |