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Molecular Profile | NRAS G12C |
Therapy | Sotorasib |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
NRAS G12C | Advanced Solid Tumor | sensitive | Sotorasib | Preclinical - Cell culture | Actionable | In a preclinical study, Lumakras (sotorasib) inhibited viability of cultured cells expressing NRAS G12C (PMID: 38236605). | 38236605 |
PubMed Id | Reference Title | Details |
---|---|---|
(38236605) | Sotorasib is a pan-RASG12C inhibitor capable of driving clinical response in NRASG12C cancers. | Full reference... |