Therapy Detail

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Therapy Name INBRX-105
Synonyms
Therapy Description

INBRX-105 (ES 101) is a bispecific antibody that binds to TNFRSF9 (CD137) and PD-L1 (CD274), potentially resulting in enhanced anti-tumor immunity and tumor cell lysis (NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
INBRX-105 INBRX105|INBRX 105|ES 101|ES-101|ES101 Immune Checkpoint Inhibitor 155 PD-L1/PD-1 antibody 106 TNFRSF9 Antibody 24 INBRX-105 (ES 101) is a bispecific antibody that binds to TNFRSF9 (CD137) and PD-L1 (CD274), potentially resulting in enhanced anti-tumor immunity and tumor cell lysis (NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03809624 Phase I INBRX-105 Study of INBRX-105 in Patients With Solid Tumors (PDL1x41BB) Recruiting USA 0


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