Clinical Trial Detail

NCT ID NCT03849651
Title TCRalphabeta-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies
Recruitment Recruiting
Gender both
Phase Phase II
Variant Requirements No
Sponsors St. Jude Children's Research Hospital
Indications

hematologic cancer

Therapies

TCR alpha/beta+/CD19+ depleted hematopoietic cells

CD45RA-depleted donor lymphocytes

anti-thymocyte globulin + Cyclophosphamide + Filgrastim + Fludarabine + Melphalan + Mesna + Thiotepa

Blinatumomab

Age Groups: adult child

No variant requirements are available.