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NCT ID NCT04003636
Title Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966) (KEYNOTE-966)
Recruitment Active, not recruiting
Gender both
Phase Phase III
Variant Requirements No
Sponsors Merck Sharp & Dohme Corp.
Indications

intrahepatic cholangiocarcinoma

gallbladder cancer

cholangiocarcinoma

Therapies

Cisplatin + Gemcitabine

Cisplatin + Gemcitabine + Pembrolizumab

Age Groups: adult | senior
Covered Countries USA | ITA | FRA | ESP | DEU | CAN | BEL

Facility Status City State Zip Country Details
University of Alabama at Birmingham Comprehensive Cancer Ctr ( Site 0016) Birmingham Alabama 35294 United States Details
University of California San Diego Moores Cancer Center ( Site 0008) La Jolla California 92093-0698 United States Details
UCLA Hematology/Oncology - Santa Monica ( Site 0014) Los Angeles California 90404 United States Details
University of California - San Francisco ( Site 0030) San Francisco California 94158 United States Details
University of Colorado Hospital ( Site 0011) Aurora Colorado 80045 United States Details
Hartford Hospital ( Site 0057) Hartford Connecticut 06102 United States Details
Yale University ( Site 0053) New Haven Connecticut 06510 United States Details
Winship Cancer Institute of Emory University ( Site 0013) Atlanta Georgia 30322-1013 United States Details
Northwest Georgia Oncology Centers PC ( Site 0045) Marietta Georgia 30060 United States Details
Decatur Memorial Hospital ( Site 0056) Decatur Illinois 62526 United States Details
Winthrop University Hospital ( Site 0059) Mineola New York 11501 United States Details
Laura and Isaac Perlmutter Cancer Center at NYU Langone Health ( Site 0038) New York New York 10016 United States Details
Columbia University/Herbert Irving Cancer Center ( Site 0009) New York New York 10032 United States Details
University of Oklahoma- Stephenson Oklahoma Cancer Center ( Site 0055) Oklahoma City Oklahoma 73104 United States Details
OHSU Center for Health & Healing ( Site 0044) Portland Oregon 97239 United States Details
Charleston Oncology ( Site 0042) Charleston South Carolina 29414 United States Details
Saint Francis Health System ( Site 0051) Greenville South Carolina 29607 United States Details
Blue Ridge Cancer Care ( Site 0033) Roanoke Virginia 24014 United States Details
CEMIC ( Site 0581) Buenos Aires Caba C1431FWO Argentina Details
Fundacion Favaloro ( Site 0578) Ciudad de Buenos Aires Caba C1093AAS Argentina Details
Centro Medico San Roque ( Site 0579) San Miguel de Tucuman Tucuman T4000IAK Argentina Details
Hospital Municipal de Gastroenterologia Dr. Bonorino Udaondo ( Site 0580) Caba C1264AAA Argentina Details
Centro Oncologico Riojano Integral ( Site 0584) La Rioja F5300COE Argentina Details
Liverpool Hospital ( Site 0707) Liverpool New South Wales 2170 Australia Details
Mid North Coast Cancer Institute ( Site 0708) Port Macquarie New South Wales 2444 Australia Details
Gallipoli Medical Research Foundation ( Site 0705) Brisbane Queensland 4120 Australia Details
Eastern Health ( Site 0704) Box Hill Victoria 3128 Australia Details
Western Health-Sunshine Hospital ( Site 0709) St Albans Victoria 3021 Australia Details
UZA University Hospital Antwerp ( Site 0202) Edegem Antwerpen 2650 Belgium Details
Saint-Luc UCL ( Site 0200) Brussels Bruxelles-Capitale, Region De 1200 Belgium Details
Erasme Hospital ( Site 0204) Bruxelles Bruxelles-Capitale, Region De 1070 Belgium Details
Grand Hopital de Charleroi ( Site 0206) Charleroi Hainaut 6000 Belgium Details
CHU de Liege ( Site 0201) Liège Liege 4000 Belgium Details
UZ Gent ( Site 0203) Gent Oost-Vlaanderen 9000 Belgium Details
UZ Leuven ( Site 0205) Leuven Vlaams-Brabant 3000 Belgium Details
Oncobio Servicos de Saude SA ( Site 0604) Nova Lima Minas Gerais 34000-000 Brazil Details
Hospital de Caridade de Ijui ( Site 0602) Ijui Rio Grande Do Sul 98700-000 Brazil Details
Associacao Hospitalar Moinhos de Vento ( Site 0599) Porto Alegre Rio Grande Do Sul 90035-001 Brazil Details
Hospital de Clinicas de Porto Alegre ( Site 0610) Porto Alegre Rio Grande Do Sul 90035-903 Brazil Details
Hospital Nossa Senhora da Conceicao ( Site 0601) Porto Alegre Rio Grande Do Sul 91350-200 Brazil Details
Instituto COI de Pesquisa Educacao e Gestao ( Site 0606) Rio de Janeiro 22793-080 Brazil Details
Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0607) Sao Paulo 01246-000 Brazil Details
Hospital Paulistano - Amil Clinical Research ( Site 0603) Sao Paulo 01321-001 Brazil Details
Real e Benemerita Associacao Portuguesa de Beneficencia ( Site 0609) Sao Paulo 01321-001 Brazil Details
A.C. Camargo Cancer Center ( Site 0600) Sao Paulo 01509-900 Brazil Details
Tom Baker Cancer Centre ( Site 0184) Calgary Alberta T2N 4N2 Canada Details
Cross Cancer Institute ( Site 0183) Edmonton Alberta T6G 1Z2 Canada Details
Hamilton Health Sciences-Juravinski Cancer Centre ( Site 0182) Hamilton Ontario L8V5C2 Canada Details
Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0180) Montreal Quebec H2X 3E4 Canada Details
McGill University Health Centre ( Site 0179) Montreal Quebec H4A 3J1 Canada Details
Centro Investigación del Cáncer James Lind ( Site 0622) Temuco Araucania 4780000 Chile Details
IC La Serena Research ( Site 0630) La Serena Coquimbo 1720430 Chile Details
Servicios Medicos Urumed ( Site 0621) Rancagua Lbtdr Gen Bernardo O Higgins 2852424 Chile Details
Fundacion Arturo Lopez Perez FALP ( Site 0623) Santiago Region M. De Santiago 7500921 Chile Details
Sociedad Oncovida S.A. ( Site 0626) Santiago Region M. De Santiago 7510032 Chile Details
Pontificia Universidad Catolica de Chile ( Site 0620) Santiago Region M. De Santiago 8330032 Chile Details
Anhui Provincial Hospital ( Site 0140) Hefei Anhui 230001 China Details
Beijing Cancer Hospital ( Site 0138) Beijing Beijing 100036 China Details
Peking Union Medical College Hospital ( Site 0150) Beijing Beijing 100730 China Details
First Affiliated Hospital of The Third Military Medical University ( Site 0130) Chongqing Chongqing 400038 China Details
Fujian Provincial Cancer Hospital ( Site 0154) Fuzhou Fujian 350014 China Details
900 Hospital of the Joint ( Site 0137) Fuzhou Fujian 350025 China Details
Guangdong Provincial People s Hospital ( Site 0161) Guangzhou Guangdong 510080 China Details
The Third Xiangya Hospital of Central South University ( Site 0157) Changsha Hainan 410013 China Details
Harbin Medical University Cancer Hospital ( Site 0133) Harbin Heilongjiang 610000 China Details
Hunan Provincial People Hospital ( Site 0142) Changsha Hunan 410005 China Details
Hunan Cancer Hospital ( Site 0132) Changsha Hunan 410013 China Details
The 81st Hospital of PLA ( Site 0128) Nanjing Jiangsu 210031 China Details
The First Hospital of Jilin University ( Site 0131) Chanchun Jilin 130021 China Details
Zhongshan Hospital Fudan University ( Site 0129) Shanghai Shanghai 200032 China Details
Renji Hospital Shanghai Jiaotong University School of Medicine ( Site 0158) Shanghai Shanghai 200127 China Details
Fudan University Shanghai Cancer Center ( Site 0160) Shanghai Shanghai 201315 China Details
Tangdu Hospital ( Site 0146) XI An Shanxi 710038 China Details
The First Affiliated Hospital of Xi an Jiaotong University ( Site 0145) XI An Shanxi 710048 China Details
West China Hospital of Sichuan University ( Site 0147) Chengdu Sichuan 610041 China Details
Tianjin Medical University Cancer Institute & Hospital ( Site 0155) Tianjin Tianjin 300060 China Details
The First Affiliated Hospital Zhejiang University ( Site 0136) Hangzhou Zhejiang 310003 China Details
Zhejiang Cancer Hospital ( Site 0134) Hangzhou Zhejiang 310022 China Details
CHU Bordeaux Haut-Leveque Centre Francois Magendie ( Site 0245) Pessac Cedex Gironde 33604 France Details
A.P.H. Paris, Hopital Beaujon ( Site 0247) Clichy Hauts-de-Seine 92110 France Details
CHU de Montpellier - Hopital Saint-Eloi ( Site 0248) Montpellier Herault 34295 France Details
Centre Eugene Marquis ( Site 0242) Rennes Ille-et-Vilaine 35042 France Details
CHU Clermont-Ferrand - Site Estaing ( Site 0249) Clermont-Ferrand Puy-de-Dome 63003 France Details
Gustave Roussy ( Site 0244) Villejuif Val-de-Marne 94805 France Details
Universitaetsklinikum Ulm ( Site 0267) Ulm Baden-Wurttemberg 89081 Germany Details
Klinikum der Ludwig - Maximilian Universitat Munchen ( Site 0264) Muenchen Bayern 81377 Germany Details
Krankenhaus Nordwest ( Site 0266) Frankfurt Hessen 60488 Germany Details
Medizinische Hochschule Hannover ( Site 0265) Hannover Niedersachsen 30625 Germany Details
Universitaetsklinikum Aachen AOER ( Site 0275) Aachen Nordrhein-Westfalen 52074 Germany Details
Universitaetsklinikum Essen ( Site 0273) Essen Nordrhein-Westfalen 45147 Germany Details
Universitaetsklinikum Koeln ( Site 0274) Koeln Nordrhein-Westfalen 50937 Germany Details
Universitaetsklinikum Magdeburg A.o.R. ( Site 0271) Magdeburg Sachsen-Anhalt 39120 Germany Details
Staedtisches Klinikum Dresden ( Site 0272) Dresden Sachsen 01067 Germany Details
Charite - Universtitatsmedizin Berlin CCM ( Site 0269) Berlin 10117 Germany Details
Universitaetsklinikum Hamburg-Eppendorf ( Site 0268) Hamburg 20246 Germany Details
Pamela Youde Nethersole Eastern Hospital ( Site 0857) Hong Kong Hong Kong Details
Prince of Wales Hospital ( Site 0855) Hong Kong Hong Kong Details
Princess Margaret Hospital. ( Site 0856) Hong Kong Hong Kong Details
Queen Mary Hospital ( Site 0851) Hong Kong Hong Kong Details
Queen Elizabeth Hospital. ( Site 0854) Kowloon Hong Kong Details
Cork University Hospital ( Site 0538) Cork T12 DC4A Ireland Details
Bon Secours Hospital ( Site 0526) Cork T12 DV56 Ireland Details
Tallaght University Hospital ( Site 0522) Dublin D24 NROA Ireland Details
St Vincents University Hospital ( Site 0521) Dublin DO4 YN63 Ireland Details
Rambam Medical Center ( Site 0308) Haifa 3109601 Israel Details
Hadassah Ein Karem - Sharett Institute of Oncology ( Site 0309) Jerusalem 9112001 Israel Details
Rabin Medical Center ( Site 0307) Petah Tikva 4941492 Israel Details
Sourasky Medical Center ( Site 0306) Tel Aviv 6423906 Israel Details
Universita Cattolica del Sacro Cuore - Policlinico Gemelli ( Site 0329) Rome Abruzzo 00168 Italy Details
Policlinico S. Orsola-Malpighi ( Site 0333) Bologna 40138 Italy Details
A.O. di Rilievo Nazionale e di alta Specializzazione Garibaldi ( Site 0330) Catania 95124 Italy Details
ASST Grande Ospedale Metropolitano Niguarda ( Site 0332) Milano 20162 Italy Details
Azienda Ospedaliero Universitaria Pisana ( Site 0326) Pisa 56127 Italy Details
Policlinico Universitario Campus Biomedico ( Site 0328) Roma 00128 Italy Details
Azienda Ospedaliera Universitaria di Verona ( Site 0334) Verona 37134 Italy Details
Aichi Cancer Center Hospital ( Site 0080) Nagoya Aichi 464-8681 Japan Details
National Cancer Center Hospital East ( Site 0081) Kashiwa Chiba 277-8577 Japan Details
Kobe City Medical Center General Hospital ( Site 0087) Kobe Hyogo 650-0047 Japan Details
Kagawa University Hospital ( Site 0086) Kita-gun Kagawa 761-0793 Japan Details
Kanagawa Cancer Center ( Site 0079) Yokohama Kanagawa 241-8515 Japan Details
Osaka University Hospital ( Site 0085) Suita Osaka 565-0871 Japan Details
Kyorin University Hospital ( Site 0077) Mitaka Tokyo 181-8611 Japan Details
National Hospital Organization Kyushu Cancer Center ( Site 0078) Fukuoka 811-1395 Japan Details
Kyoto University Hospital ( Site 0083) Kyoto 606-8507 Japan Details
Osaka International Cancer Institute ( Site 0084) Osaka 541-8567 Japan Details
The Cancer Institute Hospital of JFCR ( Site 0082) Tokyo 135-8550 Japan Details
Chonnam National University Hwasun Hospital ( Site 0837) Hwasun Gun Jeonranamdo 58128 Korea, Republic of Details
Seoul National University Bundang Hospital ( Site 0833) Seongnam-si Kyonggi-do 13605 Korea, Republic of Details
CHA Bundang Medical Center CHA University ( Site 0835) Seongnam Kyonggi-do 13496 Korea, Republic of Details
Ajou University Hospital, Clinical Research Center ( Site 0838) Suwon-si Kyonggi-do 16499 Korea, Republic of Details
Kyungpook National University Chilgok Hospital ( Site 0834) Daegu Taegu-Kwangyokshi 41404 Korea, Republic of Details
Chungnam National University Hospital ( Site 0840) Daejeon Taejon-Kwangyokshi 35015 Korea, Republic of Details
Severance Hospital Yonsei University Health System ( Site 0836) Seoul 03722 Korea, Republic of Details
Asan Medical Center ( Site 0830) Seoul 05505 Korea, Republic of Details
Samsung Medical Center ( Site 0831) Seoul 06351 Korea, Republic of Details
The Catholic University of Korea. Seoul St. Mary s Hospital ( Site 0839) Seoul 06591 Korea, Republic of Details
Korea University Guro Hospital ( Site 0832) Seoul 08308 Korea, Republic of Details
Hospital Sultan Ismail ( Site 0772) Johor Bahru Johor 81100 Malaysia Details
University Malaya Medical Centre ( Site 0770) Lembah Pantai Kuala Lumpur 59100 Malaysia Details
Hospital Pulau Pinang ( Site 0773) Georgetown Pulau Pinang 10990 Malaysia Details
Institut Kanser Negara - National Cancer Institute ( Site 0767) Putrajaya Wilayah Persekutuan Putrajaya 62250 Malaysia Details
Hospital Kuala Lumpur ( Site 0768) Kuala Lumpur 50586 Malaysia Details
Pantai Hospital Kuala Lumpur ( Site 0771) Kuala Lumpur 59100 Malaysia Details
Maastricht University Medical Centre ( Site 0347) Maastricht Limburg 6229 HX Netherlands Details
AMC ( Site 0348) Amsterdam Noord-Holland 1105 AZ Netherlands Details
Erasmus University Medical Center ( Site 0352) Rotterdam Zuid-Holland 3015 GD Netherlands Details
UMCG ( Site 0349) Groningen 9713 GZ Netherlands Details
Universitair Medisch Centrum Utrecht ( Site 0351) Utrecht 3584 CX Netherlands Details
Auckland City Hospital ( Site 0725) Auckland 1023 New Zealand Details
Hospital Universitario General de Asturias ( Site 0434) Oviedo Asturias 33011 Spain Details
Hospital General Universitari Vall d Hebron ( Site 0432) Barcelona 08035 Spain Details
Hospital General Universitario Gregorio Maranon ( Site 0433) Madrid 28009 Spain Details
Hospital Universitario HM Sanchinarro ( Site 0435) Madrid 28050 Spain Details
Hospital Regional Universitario Carlos Haya ( Site 0431) Malaga 29010 Spain Details
Taipei Veterans General Hospital ( Site 0861) Taipei, Taipei 112 Taiwan Details
Chang Gung Medical Foundation. Kaohsiung Branch ( Site 0865) Kaohsiung 833 Taiwan Details
China Medical University Hospital ( Site 0862) Taichung 40447 Taiwan Details
National Cheng Kung University Hospital ( Site 0864) Tainan 704 Taiwan Details
National Taiwan University Hospital ( Site 0860) Taipei 10048 Taiwan Details
Koo Foundation Sun Yat-Sen Cancer Center ( Site 0863) Taipei 112 Taiwan Details
Chang Gung Medical Foundation. Linkou ( Site 0853) Taoyuan 333 Taiwan Details
King Chulalongkorn Memorial Hospital ( Site 0884) Bangkok Krung Thep Maha Nakhon 10330 Thailand Details
Ramathibodi Hospital. ( Site 0889) Bangkok Krung Thep Maha Nakhon 10400 Thailand Details
Siriraj Hospital ( Site 0888) Bangkok Krung Thep Maha Nakhon 10700 Thailand Details
Sunpasithiprasong Hospital ( Site 0883) Ubonratchathani Ubon Ratchathani 34000 Thailand Details
Maharaj Nakorn Chiang Mai Hospital ( Site 0887) Chiang Mai 50200 Thailand Details
Srinagarind Hospital ( Site 0885) Khon Kaen 40002 Thailand Details
Udon Thani Cancer Hospital ( Site 0886) Udon Thani 41330 Thailand Details
Inonu Universitesi Medical Fakultesi ( Site 0501) Malatya Adana 44280 Turkey Details
Baskent University Adana Training Hospital ( Site 0499) Adana 01250 Turkey Details
Hacettepe University Faculty of Medicine ( Site 0498) Ankara 06100 Turkey Details
Abdurrahman Yurtaslan Onkoloji Hastanesi ( Site 0494) Ankara 06200 Turkey Details
Gazi Universitesi Tip Fakultesi ( Site 0496) Ankara 06500 Turkey Details
Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 0506) Istanbul 34098 Turkey Details
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 0495) Istanbul 34722 Turkey Details
Izmir Medical Park Hospital Department of Medical Oncology ( Site 0502) Izmir 35520 Turkey Details
Erciyes Universitesi Tip Fakultesi ( Site 0500) Kayseri 38039 Turkey Details
Aberdeen Royal Infirmary ( Site 0529) Aberdeen Aberdeen City AB252ZN United Kingdom Details
Royal Free London NHS Foundation Trust ( Site 0520) London London, City Of NW3 2QG United Kingdom Details
Royal Marsden Hospital ( Site 0536) London London, City Of SW3 6JJ United Kingdom Details
Imperial College Healthcare NHS Trust - Hammersmith Hospital ( Site 0525) London London, City Of W12 0HS United Kingdom Details
Royal Marsden NHS Foundation Trust ( Site 0535) Sutton Surrey SM2 5PT United Kingdom Details
Belfast City Hospital ( Site 0517) Belfast BT9 7AB United Kingdom Details
University Hospital Coventry and Warwickshire NHS Trust ( Site 0518) Coventry CV2 2DX United Kingdom Details
The Christie NHS Foundation Trust ( Site 0537) Manchester M20 4BX United Kingdom Details
*Shaded cells indicate that there was no data available from clincialtrials.gov for the field