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| NCT ID | NCT04420884 |
| Title | TAK-676 as Single Agent (SA) and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors |
| Acronym | iintune-1 |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | No |
| Sponsors | Millennium Pharmaceuticals, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | GBR | FRA | CAN | BEL | AUT |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| University of California San Diego Moores Cancer Center | RECRUITING | La Jolla | California | 92093 | United States | Details |
| Norris Comprehensive Cancer Center | RECRUITING | Los Angeles | California | 90089-1019 | United States | Details |
| UCI Health - Chao Family Comprehensive Cancer Center | NOT_YET_RECRUITING | Orange | California | 92868 | United States | Details |
| University of California Los Angeles - Jonsson Comprehensive Cancer Center | RECRUITING | Santa Monica | California | 90404-2023 | United States | Details |
| SCRI - HealthOne Denver | RECRUITING | Denver | Colorado | 80218-1238 | United States | Details |
| Yale Cancer Center | RECRUITING | New Haven | Connecticut | 06519 | United States | Details |
| Memorial Cancer Institute at Memorial Hospital West - Cancer Institute/Radiology Oncology | NOT_YET_RECRUITING | Gainesville | Florida | 32610 | United States | Details |
| Orlando Health Cancer Institute | NOT_YET_RECRUITING | Orlando | Florida | 32806 | United States | Details |
| Robert H. Lurie Comprehensive Cancer Center of Northwestern University | NOT_YET_RECRUITING | Chicago | Illinois | 60611 | United States | Details |
| University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center | RECRUITING | Baltimore | Maryland | 21201-1544 | United States | Details |
| Massachusetts General Hospital | RECRUITING | Boston | Massachusetts | 02114 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Barbara Ann Karmanos Cancer Institute - Lawrence and Idell Weisberg Cancer Treatment Center | RECRUITING | Detroit | Michigan | 48201-2013 | United States | Details |
| Siteman Cancer Center - West County | RECRUITING | Creve Coeur | Missouri | 63141 | United States | Details |
| Siteman Cancer Center - North County | RECRUITING | Florissant | Missouri | 63031 | United States | Details |
| Washington University School of Medicine Siteman Cancer Center | RECRUITING | Saint Louis | Missouri | 63110-1032 | United States | Details |
| Siteman Cancer Center - South County | RECRUITING | Saint Louis | Missouri | 63129 | United States | Details |
| Siteman Cancer Center - St. Peters | RECRUITING | Saint Peters | Missouri | 63376 | United States | Details |
| University of Cincinnati Health Barrett Cancer Center | RECRUITING | Cincinnati | Ohio | 45019 | United States | Details |
| University of Cincinnati Health Barrett Cancer Center | RECRUITING | Cincinnati | Ohio | 45219-2354 | United States | Details |
| West Chester Hospital | RECRUITING | West Chester | Ohio | 45069 | United States | Details |
| Providence Portland Medical Center | RECRUITING | Portland | Oregon | 97213 | United States | Details |
| Fox Chase Cancer Center | RECRUITING | Philadelphia | Pennsylvania | 19111 | United States | Details |
| University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center | RECRUITING | Pittsburgh | Pennsylvania | 15232 | United States | Details |
| Sarah Cannon Research Institute (SCRI) | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Mary Crowley Cancer Research | RECRUITING | Dallas | Texas | 75230 | United States | Details |
| Virginia Cancer Specialists, P.C. - Fairfax | RECRUITING | Fairfax | Virginia | 22031-2171 | United States | Details |
| Klinikum Wels-Grieskirchen | RECRUITING | Wels | Oberoesterreich | 4600 | Austria | Details |
| Landeskrankenhaus Salzburg | RECRUITING | Salzburg | 5020 | Austria | Details | |
| Landesklinikum Wiener Neustadt | RECRUITING | Wiener Neustadt | 2700 | Austria | Details | |
| Universitair Ziekenhuis Antwerpen | NOT_YET_RECRUITING | Edegem | 2650 | Belgium | Details | |
| Universitair Ziekenhuis Leuven - Campus Gasthuisberg | NOT_YET_RECRUITING | Leuven | 3000 | Belgium | Details | |
| Cross Cancer Institute | RECRUITING | Edmonton | Alberta | T6G 1Z2 | Canada | Details |
| McMaster University Medical Center | NOT_YET_RECRUITING | Hamilton | Ontario | L8N 3Z5 | Canada | Details |
| Princess Margaret Cancer Centre | RECRUITING | Toronto | Ontario | M5G 2M9 | Canada | Details |
| Jewish General Hospital | NOT_YET_RECRUITING | Montreal | Quebec | H3T 1E2 | Canada | Details |
| McGill University Health Centre | NOT_YET_RECRUITING | Montreal | Quebec | H4A 3J1 | Canada | Details |
| Beijing Cancer Hospital | RECRUITING | Beijing | Beijing Sheng | 100142 | China | Details |
| Sixth Affiliated Hospital of Sun Yat-Sen University/Guangdong Gastrointestinal Hospital | NOT_YET_RECRUITING | Guangzhou | Guangzhou Sheng | 510655 | China | Details |
| Fudan University Shanghai Cancer Center | NOT_YET_RECRUITING | Shanghai | Shanghai | 200025 | China | Details |
| Shanghai East Hospital | NOT_YET_RECRUITING | Shanghai | Shanghai | 200123 | China | Details |
| West China School of Medicine - West China Hospital of Sichuan University | RECRUITING | Chengdu | Sichuan Sheng | 610610 | China | Details |
| West China Hospital | NOT_YET_RECRUITING | Chengdu | Sichuan | 610041 | China | Details |
| Zhejiang Cancer Hospital | NOT_YET_RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Hopital Foch | RECRUITING | Suresnes | Ile-de-France | 92150 | France | Details |
| Institut de Cancerologie de Lorraine | RECRUITING | Vandœuvre-les-Nancy | Meurthe-et-Moselle | 54519 | France | Details |
| Centre Hospitalier Regional et Universitaire de Besancon - Hopital Jean-Minjoz | RECRUITING | Besancon | 25000 | France | Details | |
| Hopital Saint-Andre | RECRUITING | Bordeaux | 33000 | France | Details | |
| Centre Francois Baclesse | RECRUITING | Caen | 14000 | France | Details | |
| Centre Georges Francois Leclerc | RECRUITING | Dijon | 21079 | France | Details | |
| Centre de Lutte contre le Cancer - Centre Oscar Lambret | RECRUITING | Lille | 59000 | France | Details | |
| Centre Leon Berard | RECRUITING | Lyon | 69008 | France | Details | |
| Hopital de la Timone | RECRUITING | Marseille | 13385 | France | Details | |
| Hopital Saint-Antoine | RECRUITING | Paris | 75012 | France | Details | |
| Institut de Cancerologie de lOuest - Saint-Herblain - Site Rene Gauducheau | RECRUITING | St Herblain | 44805 | France | Details | |
| Gustave Roussy | RECRUITING | Villejuif | 94805 | France | Details | |
| Soroka Medical Center | RECRUITING | Beer Sheva | 9457108 | Israel | Details | |
| Hadassah University Hospital Ein Kerem | RECRUITING | Jerusalem | 9112001 | Israel | Details | |
| Tel Aviv Sourasky Medical Center | RECRUITING | Tel Aviv-Yafo | 64239 | Israel | Details | |
| The Chaim Sheba Medical Center | RECRUITING | Tel Hashomer | 52621 | Israel | Details | |
| National Cancer Center Hospital | RECRUITING | Chuo-Ku | Tokyo | 104-0045 | Japan | Details |
| Centrum Onkologii Im. Prof. F. Lukaszczyka w Bydgoszczy | RECRUITING | Bydgoszcz | Kujawsko-Pomorskie | 85-796 | Poland | Details |
| Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy | RECRUITING | Warsaw | Mazowieckie | 02-034 | Poland | Details |
| PRCCI Site: Puerto Rico Medical Research Center Torre Medica Hospital Auxilio Mutuo | NOT_YET_RECRUITING | San Juan | 00917 | Puerto Rico | Details | |
| Fundacion de Investigacion de Diego | NOT_YET_RECRUITING | San Juan | 00927 | Puerto Rico | Details | |
| PanOncology Trials: Universidad de Puerto Rico - Centro Comprensivo de Cancer | RECRUITING | San Juan | 00936 | Puerto Rico | Details | |
| Kantonsspital Sankt Gallen | RECRUITING | St. Gallen | Saint Gallen | 9007 | Switzerland | Details |
| Inselspital Universitatsspital Bern | RECRUITING | Bern | 3010 | Switzerland | Details | |
| Hopitaux Universitaires de Geneve | RECRUITING | Geneve | 1205 | Switzerland | Details | |
| Centre Hospitalier Universitaire Vaudois Lausanne | RECRUITING | Lausanne | 1011 | Switzerland | Details | |
| The Royal Marsden NHS Foundation Trust | RECRUITING | Sutton | London | SM2 5NG | United Kingdom | Details |
| Queen's University Belfast | NOT_YET_RECRUITING | Belfast | Northern Ireland | BT9 7BL | United Kingdom | Details |
| Leeds Teaching Hospitals NHS Trust | RECRUITING | Leeds | LS9 7TF | United Kingdom | Details | |
| University College London Hospitals NHS Foundation Trust | RECRUITING | London | NW1 2BU | United Kingdom | Details | |
| The Royal Marsden NHS Foundation Trust | RECRUITING | London | SW3 6JJ | United Kingdom | Details | |
| The Christie NHS Foundation Trust | NOT_YET_RECRUITING | Manchester | M20 4BX | United Kingdom | Details | |
| Oxford University Hospitals NHS Foundation Trust | RECRUITING | Oxford | Ox1 2JD | United Kingdom | Details |