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| NCT ID | NCT05099172 |
| Title | First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2) |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | No |
| Sponsors | Bayer |
| Indications | |
| Therapies | |
| Age Groups: | adult | senior |
| Covered Countries | USA | NLD | ITA | FRA | ESP | BEL |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Banner MD Anderson Cancer Center | RECRUITING | Gilbert | Arizona | 85234 | United States | Details |
| City of Hope National Medical Center | RECRUITING | Duarte | California | 91010 | United States | Details |
| City of Hope-Cancer Department | RECRUITING | Duarte | California | 91010 | United States | Details |
| Emory University | RECRUITING | Atlanta | Georgia | 30322 | United States | Details |
| The Center for Cancer and Blood Disorders | RECRUITING | Bethesda | Maryland | 20817 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Henry Ford Health System | Brigitte Harris Cancer Pavilion | RECRUITING | Detroit | Michigan | 48202 | United States | Details |
| Roswell Park Comprehensive Cancer Center | SUSPENDED | Buffalo | New York | 14203 | United States | Details |
| NYU Langone Health | WITHDRAWN | New York | New York | 10016 | United States | Details |
| Tennessee Oncology | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| University of Texas MD Anderson Cancer Center | RECRUITING | Houston | Texas | 77030 | United States | Details |
| Virginia Cancer Specialists, PC | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| UZ Leuven Gasthuisberg | RECRUITING | Leuven | 3000 | Belgium | Details | |
| AZ Delta | Clinical Trial Center - Pneumology | RECRUITING | Roeselare | 8800 | Belgium | Details | |
| Liga Norte Riograndense Contra o Cancer | Centro de Pesquisa Clínica | RECRUITING | Natal | Rio Grande Do Norte | 59040-000 | Brazil | Details |
| Hospital de Base | Integrated Research Center | RECRUITING | São José do Rio Preto | Sao Paulo | 15090-000 | Brazil | Details |
| Hospital Israelita Albert Einstein | Morumbi - Clinical Research Department | RECRUITING | Sao Paulo | 05651-901 | Brazil | Details | |
| Fujian Cancer Hospital | RECRUITING | Fuzhou | Fujian | 350014 | China | Details |
| Harbin Medical University Cancer Hospital | RECRUITING | Harbin | Heilongjiang | 150081 | China | Details |
| Union Hospi, Tongji Med College, Huazhong Univ. Scien&Tech | RECRUITING | Wuhan | Hubei | 430023 | China | Details |
| Hunan Cancer Hospital | RECRUITING | Changsha | Hunan | 410013 | China | Details |
| NJ Drum Tower Hospital, the Affil Hos of NJ Univ Med School | RECRUITING | Nanjing | Jiangsu | 210008 | China | Details |
| Qilu Hosp., Shandong Univ. | RECRUITING | Jinan | Shandong | China | Details | |
| West China Hospital Sichuan University | RECRUITING | Chengdu | Sichuan | 610041 | China | Details |
| Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine | RECRUITING | Hangzhou | Zhejiang | 310016 | China | Details |
| Zhejiang Cancer Hospital | RECRUITING | Hangzhou | Zhejiang | 310022 | China | Details |
| Beijing Cancer Hospital | RECRUITING | Beijing | 100142 | China | Details | |
| Beijing Hospital | RECRUITING | Beijing | 100730 | China | Details | |
| Shandong University - Shandong Cancer Hospital | NOT_YET_RECRUITING | Jinan | 250117 | China | Details | |
| Shanghai Chest Hospital, Shanghai Jiaotong University | RECRUITING | Shanghai | 200030 | China | Details | |
| Zhejiang University School of Medicine - Taizhou Hospital of Zhejiang Province | NOT_YET_RECRUITING | Taizhou | 317000 | China | Details | |
| Institut Bergonié - Unicancer Nouvelle Aquitaine | RECRUITING | Bordeaux Cedex | 33076 | France | Details | |
| Centre Léon Bérard | RECRUITING | Lyon | 69008 | France | Details | |
| Assistance Publique Hopitaux de Marseille (AP-HM) - Hopital Nord | NOT_YET_RECRUITING | Marseille | 13915 | France | Details | |
| Hôpital Nord Laennec - Oncologie médicale thoracique et digestive | NOT_YET_RECRUITING | Nantes | 44093 | France | Details | |
| Institut Curie - Ulm - Paris | RECRUITING | PARIS cedex 5 | 75248 | France | Details | |
| Institut de Cancérologie de l'Ouest - Saint Herblain | RECRUITING | Saint-Herblain | 44800 | France | Details | |
| Institut Gustave Roussy - Département de Médecine Oncologique | RECRUITING | Villejuif Cedex | 94805 | France | Details | |
| Queen Mary Hospital | RECRUITING | Hong Kong | Hong Kong | Details | ||
| Hong Kong United Oncology Centre | NOT_YET_RECRUITING | Kowloon | 0 | Hong Kong | Details | |
| Prince of Wales Hospital | RECRUITING | Shatin | Hong Kong | Details | ||
| Clalit Health Services Rabin Medical Center-Beilinson Campus | RECRUITING | Petah Tikva | 4941492 | Israel | Details | |
| Chaim Sheba Medical Center | RECRUITING | Ramat Gan | 5266202 | Israel | Details | |
| Istituto Nazionale Tumori IRCCS Fondazione G.Pascale | WITHDRAWN | Napoli | Campania | 80131 | Italy | Details |
| A.O.U. di Parma | RECRUITING | Parma | Emilia-Romagna | 43126 | Italy | Details |
| IRCCS Centro di Riferimento Oncologico (CRO) | RECRUITING | Pordenone | Friuli-Venezia Giulia | 33081 | Italy | Details |
| Fondazione Policlinico Universitario Agostino Gemelli IRCCS | RECRUITING | Roma | Lazio | 00168 | Italy | Details |
| Istituto Clinico Humanitas - Humanitas Mirasole S.p.A. | RECRUITING | Milano | Lombardia | 20089 | Italy | Details |
| Fondazione IRCCS Istituto Nazionale dei Tumori | RECRUITING | Milano | Lombardia | 20133 | Italy | Details |
| IRCCS Istituto Europeo di Oncologia s.r.l. (IEO) | RECRUITING | Milano | Lombardia | 20141 | Italy | Details |
| A.O.U. San Luigi Gonzaga | RECRUITING | Torino | Piemonte | 10043 | Italy | Details |
| Azienda Ospedaliera Universitaria Integrata Verona (AOUI) | NOT_YET_RECRUITING | Verona | 37126 | Italy | Details | |
| Aichi Cancer Center Hospital | RECRUITING | Nagoya | Aichi | 464-8681 | Japan | Details |
| National Cancer Center Hospital East | RECRUITING | Kashiwa | Chiba | 277-8577 | Japan | Details |
| National Hospital Organization Shikoku Cancer Center | RECRUITING | Matsuyama | Ehime | 791-0280 | Japan | Details |
| Hokkaido University Hospital | RECRUITING | Sapporo | Hokkaido | 060-8648 | Japan | Details |
| Kanagawa Cancer Center | RECRUITING | Yokohama | Kanagawa | 241-8515 | Japan | Details |
| Okayama University Hospital | RECRUITING | Okayama-city | Okayama | 700-8558 | Japan | Details |
| Shizuoka Cancer Center | RECRUITING | Sunto | Shizuoka | 411-8777 | Japan | Details |
| National Cancer Center Hospital | RECRUITING | Chuo-ku | Tokyo | 104-0045 | Japan | Details |
| Tottori University Hospital | RECRUITING | Yonago | Tottori | 683-8504 | Japan | Details |
| Kindai University Hospital | NOT_YET_RECRUITING | Osakasayama-shi | 589-8511 | Japan | Details | |
| Osaka International Cancer Institute | RECRUITING | Osaka | 541-8567 | Japan | Details | |
| Chungbuk National University Hospital | RECRUITING | Cheongju-si | Chungcheongbugdo | 28644 | Korea, Republic of | Details |
| Seoul National University Bundang Hospital | RECRUITING | Seongnam-si | Gyeonggido | 13620 | Korea, Republic of | Details |
| St.Vincent's Hospital | RECRUITING | Suwon-si | Gyeonggido | 442-723 | Korea, Republic of | Details |
| Seoul National University Hospital | RECRUITING | Seoul | Seoul Teugbyeolsi | 3080 | Korea, Republic of | Details |
| Severance Hospital, Yonsei University Health System | RECRUITING | Seoul | 03722 | Korea, Republic of | Details | |
| Asan Medical Center | RECRUITING | Seoul | 138-736 | Korea, Republic of | Details | |
| Samsung Medical Center | NOT_YET_RECRUITING | Seoul | 6351 | Korea, Republic of | Details | |
| Nederlands Kanker Instituut | RECRUITING | Amsterdam | 1066 CX | Netherlands | Details | |
| Radboud University Medical Center | Afdeling Interne Geneeskunde | NOT_YET_RECRUITING | Nijmegen | 6500 HB | Netherlands | Details | |
| Erasmus Medisch Centrum | RECRUITING | Rotterdam | 3015 GD | Netherlands | Details | |
| Uniwersyteckie Centrum Kliniczne | RECRUITING | Gdansk | 80-214 | Poland | Details | |
| SP ZOZ USK im. WAM UM w Lodzi - Centralny Szpital Weteranow | RECRUITING | Lodz | 90-549 | Poland | Details | |
| START Lisbon, CHULN - Centro Hospitalar Universitário de Lisboa Norte | NOT_YET_RECRUITING | Lisbon | Lisboa | 1649-028 | Portugal | Details |
| CHULN - H. Sta.Maria (Centro de Investigacao Clinica) | WITHDRAWN | Lisboa | 1649-035 | Portugal | Details | |
| IPO Porto | RECRUITING | Porto | 4200-072 | Portugal | Details | |
| National University Hospital | RECRUITING | Singapore | 119074 | Singapore | Details | |
| National Cancer Center Singapore | RECRUITING | Singapore | 169610 | Singapore | Details | |
| Curie Oncology | NOT_YET_RECRUITING | Singapore | 329563 | Singapore | Details | |
| Institut Català d'Oncologia Hospitalet | RECRUITING | Hospitalet de Llobregat | Barcelona | 08907 | Spain | Details |
| Ciutat Sanitaria i Universitaria de la Vall d'Hebron | RECRUITING | Barcelona | 08023 | Spain | Details | |
| Hospital Quiron Dexeus | RECRUITING | Barcelona | 08028 | Spain | Details | |
| Fundacion Jimenez Diaz (Clinica de la Concepcion) | RECRUITING | Madrid | 28040 | Spain | Details | |
| Centro Integral Oncológico Clara Campal | RECRUITING | Madrid | 28050 | Spain | Details | |
| Hospital Universitario Virgen de la Victoria | Oncology | NOT_YET_RECRUITING | Málaga | 29010 | Spain | Details | |
| Hospital Universitari i Politècnic La Fe | RECRUITING | Valencia | 46026 | Spain | Details | |
| Chung Shan Medical University Hospital | NOT_YET_RECRUITING | Taichung | 402306 | Taiwan | Details | |
| Taichung Veterans General Hospital | RECRUITING | Taichung | 40705 | Taiwan | Details | |
| National Cheng Kung University Hospital | RECRUITING | Tainan | 704 | Taiwan | Details | |
| Chi-Mei Medical Center, Liouyine | NOT_YET_RECRUITING | Tainan | 73657 | Taiwan | Details | |
| National Taiwan University Hospital | RECRUITING | Taipei | 100 | Taiwan | Details | |
| Taipei Medical University (TMU) - Shuang Ho Hospital (SHH) | NOT_YET_RECRUITING | Taipei | 23561 | Taiwan | Details | |
| Chang Gung Memorial Hospital at Linkou | RECRUITING | Taoyuan | 33305 | Taiwan | Details |