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Therapy Name BAY2927088
Synonyms
Therapy Description

BAY2927088 is a mutant-selective EGFR inhibitor with activity against EGFR exon 20 insertions, EGFR exon 19 deletion, EGFR L858R, and EGFR C797S, which potentially results in inhibition of tumor growth (European Journal of Cancer 174 (2022): S9-S10).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BAY2927088 BAY-2927088|BAY 2927088 EGFR Inhibitor (Pan) 61 HER2 Inhibitor 41 BAY2927088 is a mutant-selective EGFR inhibitor with activity against EGFR exon 20 insertions, EGFR exon 19 deletion, EGFR L858R, and EGFR C797S, which potentially results in inhibition of tumor growth (European Journal of Cancer 174 (2022): S9-S10).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05099172 Phase I BAY2927088 First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2) Recruiting USA | NLD | ITA | FRA | ESP | BEL 10


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