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| NCT ID | NCT05462717 |
| Title | Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors |
| Recruitment | Recruiting |
| Gender | both |
| Phase | Phase I |
| Variant Requirements | No |
| Sponsors | Revolution Medicines, Inc. |
| Indications | |
| Therapies | |
| Age Groups: | senior | adult |
| Covered Countries | USA | ITA | FRA | ESP | AUS |
| Facility | Status | City | State | Zip | Country | Details |
|---|---|---|---|---|---|---|
| Highlands Oncology Group | RECRUITING | Springdale | Arkansas | 72762 | United States | Details |
| UC Irvine Cancer Center | RECRUITING | Orange | California | 92868 | United States | Details |
| UC Davis Cancer Center | RECRUITING | Sacramento | California | 95817 | United States | Details |
| UCSF | RECRUITING | San Francisco | California | 94158 | United States | Details |
| University of Miami School of Medicine Sylvester Comprehensive Cancer Center | RECRUITING | Miami | Florida | 33136 | United States | Details |
| Moffitt Cancer Center | RECRUITING | Tampa | Florida | 33612 | United States | Details |
| American Oncology Partners of Maryland | RECRUITING | Bethesda | Maryland | 20817 | United States | Details |
| Dana-Farber Cancer Institute | RECRUITING | Boston | Massachusetts | 02215 | United States | Details |
| Roswell Park Comprehensive Cancer Center | RECRUITING | Buffalo | New York | 14203 | United States | Details |
| MSK Cancer Center | RECRUITING | New York | New York | 10021 | United States | Details |
| Columbia University Irving Medical Center | RECRUITING | New York | New York | 10032 | United States | Details |
| Tennessee Oncology | RECRUITING | Nashville | Tennessee | 37203 | United States | Details |
| Next Oncology | RECRUITING | San Antonio | Texas | 78229 | United States | Details |
| START | RECRUITING | San Antonio | Texas | 78229 | United States | Details |
| Next Oncology Virginia | RECRUITING | Fairfax | Virginia | 22031 | United States | Details |
| Southside Cancer Care Centre | RECRUITING | Sydney | New South Wales | 2228 | Australia | Details |
| Peninsula & South Eastern Haematology and Oncology Group | RECRUITING | Frankston | Victoria | 3199 | Australia | Details |
| Austin Health, Olivia Newton-John Cancer Research & Wellness Centre | RECRUITING | Heidelberg | Victoria | 3084 | Australia | Details |
| South West Health Care | RECRUITING | Warrnambool | Victoria | 3280 | Australia | Details |
| NH Hospital a.s. | RECRUITING | Hořovice | 268 31 | Czechia | Details | |
| Klinika onkologie a radioterapie, Fakultni Nemocnice Hradec Kralove | RECRUITING | Hradec Králové | 50005 | Czechia | Details | |
| Onkologicka klinika, Fakultni Nemocnice Olomouc | RECRUITING | Olomouc | 77900 | Czechia | Details | |
| ICO | RECRUITING | Angers | 49055 | France | Details | |
| CHU Bordeaux Hospital Saint-Andre | RECRUITING | Bordeaux | 33000 | France | Details | |
| Centre Jean Perrin | RECRUITING | Clermont-Ferrand | 63011 | France | Details | |
| Centre Oscar Lambret | RECRUITING | Lille | 59000 | France | Details | |
| Centre Léon Bérard | RECRUITING | Lyon | 69008 | France | Details | |
| CHU Nantes | RECRUITING | Nantes | 44093 | France | Details | |
| ICANS | RECRUITING | Strasbourg | 67200 | France | Details | |
| Istituto Europeo Oncologico | RECRUITING | Milano | 20141 | Italy | Details | |
| S.C. Oncologia Falck, Dipartimento Ematologia ed Oncologia Niguarda Cancer Center | RECRUITING | Milan | 20162 | Italy | Details | |
| Istituto Nazionale Tumori Fondazione G. Pascale | RECRUITING | Napoli | 80131 | Italy | Details | |
| Azienda Ospedaliero-Universitaria San Luigi Gonzaga | RECRUITING | Orbassano | 10043 | Italy | Details | |
| Fondazione IRCCS Policlinico San Matteo | RECRUITING | Pavia | 27100 | Italy | Details | |
| Centro Ricerche Cliniche di Verona s.r.l. | RECRUITING | Verona | 37134 | Italy | Details | |
| Ajou University Hospital | RECRUITING | Suwon-si | Gyeonggi-do | 16499 | Korea, Republic of | Details |
| Korea University Hospital | RECRUITING | Seoul | 02708 | Korea, Republic of | Details | |
| Seoul National University Hospital | RECRUITING | Seoul | 3080 | Korea, Republic of | Details | |
| Severance Hospital | RECRUITING | Seoul | 3722 | Korea, Republic of | Details | |
| University Malaya Medical Centre | RECRUITING | Kuala Lumpur | 59100 | Malaysia | Details | |
| Sarawak General Hospital | RECRUITING | Kuching | 93586 | Malaysia | Details | |
| Med - Polonia Sp. z o. o. | RECRUITING | Poznań | 60-693 | Poland | Details | |
| Narodowy Instytut Onkologii | RECRUITING | Warsaw | 02-781 | Poland | Details | |
| Instytut MSF Sp zoo | RECRUITING | Łódź | 90-302 | Poland | Details | |
| MSB General Hospital | RECRUITING | Belgrade | 11000 | Serbia | Details | |
| Clinical hospital center Bezanijska Kosa | RECRUITING | Belgrade | 11071 | Serbia | Details | |
| Institute for pulmonary diseases Sremska Kamenica | RECRUITING | Sremska Kamenica | 21204 | Serbia | Details | |
| National Cancer centre Singapore | RECRUITING | Singapore | 168583 | Singapore | Details | |
| NEXT Oncology IOB Hospital Quirónsalud | RECRUITING | Barcelona | 08023 | Spain | Details | |
| ICO Hospitalet | RECRUITING | Barcelona | 08908 | Spain | Details | |
| Clínica Universidad de Navarra | RECRUITING | Madrid | 28027 | Spain | Details | |
| MD Anderson Cancer Center | RECRUITING | Madrid | 28033 | Spain | Details | |
| Hospital Universitario Fundación Jiménez Díaz | RECRUITING | Madrid | 28040 | Spain | Details | |
| Clinica Universidad de Navarra | RECRUITING | Pamplona | 31008 | Spain | Details | |
| Hospital Universitario Quirónsalud | RECRUITING | Pozuelo De Alarcón | 28223 | Spain | Details | |
| Hospital Universitario Virgen del Rocío | RECRUITING | Sevilla | 41013 | Spain | Details | |
| Hospital Universitario Miguel Servet | RECRUITING | Zaragoza | 50009 | Spain | Details | |
| E-DA hospital | RECRUITING | Kaohsiung | Yanchao District | 82445 | Taiwan | Details |
| Taipei Tzu Chi Hospital | RECRUITING | New Taipei City | 231 | Taiwan | Details | |
| National Cheng Kung University Hospital | RECRUITING | Tainan | 70457 | Taiwan | Details | |
| National Taiwan University Hospital | RECRUITING | Taipei | 10048 | Taiwan | Details | |
| Siriraj Hospital | RECRUITING | Bangkok Noi | 10700 | Thailand | Details | |
| Chiang Mai University | RECRUITING | Chiang Mai | 50200 | Thailand | Details | |
| Khon Kaen University | RECRUITING | Khon Kaen | 40002 | Thailand | Details |