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Drug Name | Oratecan |
Trade Name | |
Synonyms | Irinotecan/P-glycoprotein Inhibitor HM30181AK |
Drug Descriptions |
Oratecan is a combination drug containing irinotecan and the P-glycoprotein (P-gp) efflux pump inhibitor HM30181AK, which may decrease efflux of irinotecan leading to increased intracellular accumulation, potentially leading to increased DNA damage and tumor cell death (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C88280 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Oratecan | Oratecan | 0 | 1 |