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Drug Name CUE-101
Trade Name
Synonyms CUE101|CUE 101|anti-HPV16 E7 fusion protein CUE-101
Drug Descriptions

CUE-101 is a fusion protein consisting of an HLA-A*0201 complex linked to an HPV16 E7 epitope (aa 11-20), a reduced affinity version of interleukin-2, and an effector attenuated IgG1 Fc domain, which binds to HPV16 E7-specific T-cells, potentially activating a T-cell response against HPV16 E7-positive tumor cells (PMID: 31964784).

DrugClasses
CAS Registry Number NA
NCIT ID C162459

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Therapy Name Drugs Efficacy Evidence Clinical Trials
CUE-101 CUE-101 0 2
CUE-101 + Pembrolizumab CUE-101 Pembrolizumab 0 1


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