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Drug Name | FS222 |
Trade Name | |
Synonyms | FS-222|FS 222 |
Drug Descriptions |
FS222 is a tetravalent bispecific antibody that binds to PD-L1 (CD274) and CD137 (4-1BB), which crosslinks cytotoxic T-lymphocytes to PD-L1-expressing tumor cells, potentially resulting in CD137 mediated activation of T-cells (PMID: 32345647). |
DrugClasses | Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117 TNFRSF9 Antibody 30 |
CAS Registry Number | NA |
NCIT ID | C179635 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
FS222 | FS222 | 0 | 1 |