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Drug Name | JAB-8263 |
Trade Name | |
Synonyms | JAB8263|JAB 8263 |
Drug Descriptions |
JAB-8263 is a BET inhibitor that that binds BRD2, BRD3, BRD4, and BRDT and prevents their interaction with acetylated histones, thereby leading to altered chromatin modeling and gene expression patterns, and potentially resulting in inhibition of tumor cell growth (NCI Drug Dictionary). |
DrugClasses | BET Inhibitor (Pan) 32 |
CAS Registry Number | NA |
NCIT ID | C179628 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
JAB-8263 | JAB-8263 | 0 | 1 |