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Drug Name | AMG 256 |
Trade Name | |
Synonyms | AMG-256|AMG256|Latikafusp |
Drug Descriptions |
AMG 256 is a fusion protein comprising of mutated IL-21 fused to an antibody targeting PD-1, which binds to and inhibits PD-1 signaling, potentially leading to the restoration of the T-cell mediated immune response (NCI Thesaurus, Journal for ImmunoTherapy of Cancer 2020;8) |
DrugClasses | Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117 |
CAS Registry Number | 2552814-07-8 |
NCIT ID | C174140 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AMG 256 | AMG 256 | 0 | 1 |