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Drug Name | SAR443216 |
Trade Name | |
Synonyms | SAR-443216|SAR 443216 |
Drug Descriptions |
SAR443216 is a trispecific antibody that binds to ERBB2 (HER2), CD3, and CD28, which potentially activates CD4 and CD8 T cells, resulting in T cell-dependent cellular toxicity and anti-tumor activity against ERBB2 (HER2)-expressing tumors (Cancer Res 2021;81(13_Suppl):Abstract nr 1825). |
DrugClasses | CD3 Antibody 93 HER2 (ERBB2) Antibody 73 |
CAS Registry Number | N/A |
NCIT ID | C181934 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
SAR443216 | SAR443216 | 0 | 1 |