Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name HBI-2438
Trade Name
Synonyms HBI2438|HBI 2438
Drug Descriptions

HBI-2438 selectively inhibits KRAS G12C, leading to decreased downstream signaling and potentially resulting in decreased tumor cell proliferation and inhibition of tumor growth (NCI Drug DIctionary, Mol Cancer Ther (2023) 22 (12_Supplement): A097).

DrugClasses KRAS G12C inhibitor 33
CAS Registry Number NA
NCIT ID C190135

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
HBI-2376 + HBI-2438 HBI-2376 HBI-2438 0 0
HBI-2438 HBI-2438 0 1


Additional content available in CKB BOOST