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Drug Name ABL503
Trade Name
Synonyms ABL-503|ABL 503
Drug Descriptions

ABL503 is a bispecific antibody that targets both CD274 (PD-L1) and TNFRSF9 (4-1BB), leading to activation of TNFRSF9 (4-1BB) and decreased CD274 (PD-L1) signaling, potentially resulting in activation of an antitumor immune response and inhibition of tumor growth (PMID: 34230109).

DrugClasses PD-L1/PD-1 antibody 117 TNFRSF9 Antibody 30
CAS Registry Number NA
NCIT ID C179637

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABL503 ABL503 0 1


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