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Drug Name Trastuzumab rezetecan
Trade Name
Synonyms SHR A1811|SHRA1811|SHR-A1811
Drug Descriptions

Trastuzumab rezetecan (SHR-A1811) is an antibody-drug conjugate (ADC) comprising an ERBB2 (HER2)-targeting antibody linked to the camptothecin derivative rezetecan, which potentially induces DNA damage and apoptosis in ERBB2 (HER2)-expressing tumor cells and inhibits tumor growth (NCI Drug Dictionary, Cancer Res (2023) 83 (8_Supplement): LB031).

DrugClasses HER2 (ERBB2) Antibody 73 HER2 (ERBB2) Antibody-Drug Conjugate 27
CAS Registry Number NA
NCIT ID C178312

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Trastuzumab rezetecan Trastuzumab rezetecan 0 1


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