Drug Detail


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Drug Name ENMD-2076
Trade Name
Drug Descriptions

ENMD-2076 has selective inhibitory activity against Aurora kinase A and FLT3, with reduced potency against RET, KDR (VEGFR2), FGFR1, and FGFR2, preventing angiogenesis and decreasing cell proliferation (PMID: 21177375, PMID: 22921155, PMID: 32154962).

DrugClasses Aurka Inhibitors 24 FGFR1 Inhibitor 24 FGFR2 Inhibitor 18 FLT3 Inhibitor 60 RET Inhibitor 45 VEGFR2 Inhibitor 35
CAS Registry Number 934353-76-1
NCIT ID C78190


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ENMD-2076 ENMD-2076 1 4

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