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Drug Name ENMD-2076
Trade Name
Synonyms ENMD 2076|ENMD2076
Drug Descriptions

ENMD-2076 has selective inhibitory activity against Aurora kinase A and FLT3, with reduced potency against RET, KDR (VEGFR2), FGFR1, and FGFR2, preventing angiogenesis and decreasing cell proliferation (PMID: 21177375, PMID: 22921155, PMID: 32154962).

DrugClasses Aurka Inhibitors 26 FGFR1 Inhibitor 28 FGFR2 Inhibitor 23 FLT3 Inhibitor 66 RET Inhibitor 52 VEGFR2 Inhibitor 37
CAS Registry Number 1453868-32-0
NCIT ID C78190


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ENMD-2076 ENMD-2076 2 4

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