Drug Detail


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Drug Name Linifanib
Trade Name
Synonyms ABT-869|AL-39324
Drug Descriptions

Linifanib (ABT-869) is a receptor tyrosine kinase inhibitor with specificity against FLT1 (VEGFR1), CSF-1R, KDR (VEGFR2), FLT3, and KIT, which may result in inhibition of cell proliferation and tumor growth, and tumor regression (PMID: 16648571).

DrugClasses CSF1R Inhibitor 28 FLT3 Inhibitor 66 KIT Inhibitor 57 PDGFR-beta Inhibitor 14 VEGFR Inhibitor (Pan) 36
CAS Registry Number 796967-16-3
NCIT ID C71759


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Linifanib + Paclitaxel Carboplatin Linifanib Paclitaxel 0 0
Linifanib Linifanib 8 0

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