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Drug Name Galeterone
Trade Name
Synonyms TOK-001|VN-124
Drug Descriptions

Galeterone functions both as an inhibitor of CYP17A1 and anti-androgen, as it binds the androgen receptor, acting as an competitive antagonist and also preventing Ar protein binding to chromatin and enhancing degradation of mutant Ar protein (PMID: 24874833, PMID: 31653008).

DrugClasses Hormone - Anti-androgens 48
CAS Registry Number 851983-85-2
NCIT ID C84866

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Galeterone Galeterone 0 3
Galeterone + Gemcitabine Galeterone Gemcitabine 0 1


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