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Drug Name CB-5083
Trade Name
Synonyms CB5083|CB 5083
Drug Descriptions

CB-5083 binds to and inhibits valosin-containing protein (VCP, p97) to activate the unfolded protein response, resulting in ER stress, apoptosis, and decreased tumor cell proliferation (PMID: 28878026, PMID: 29314493, PMID: 30606672, PMID: 30591537, PMID: 32655822).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
CB-5083 CB-5083 1 2
CB-5083 + Dexamethasone CB-5083 Dexamethasone 0 1

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