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ALT-801 is comprised of IL-2 fused to a T-cell receptor domain that targets p53, potentially enhancing immune response to p53-expressing tumor cells and resulting in increased tumor cell death (PMID: 21994418).
|DrugClasses||p53 Vaccine 5|
|CAS Registry Number||1188450-53-4|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|ALT-801 + Gemcitabine||ALT-801 Gemcitabine||0||1|