Drug Detail


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Drug Name Tarextumab
Trade Name
Synonyms OMP-59R5|OMP-59R5
Drug Descriptions

Tarextumab (OMP-59R5) is a monoclonal antibody that binds Notch2 and Notch3 to prevent ligand interaction, which may inhibit angiogenesis and tumor growth (PMID: 25934888, PMID: 30591982).

DrugClasses NOTCH2 Antibody 3 NOTCH3 Antibody 2
CAS Registry Number 1359940-55-8
NCIT ID C95719


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Gemcitabine + Nab-paclitaxel + Tarextumab Gemcitabine Nab-paclitaxel Tarextumab 0 0
Gemcitabine + Tarextumab Gemcitabine Tarextumab 0 0
Tarextumab Tarextumab 0 2

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