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Drug Name Tirapazamine
Trade Name Tirazone
Synonyms SR4233|WIN 59075
Drug Descriptions

Tirazone (tirapazamine) is a hypoxia-activated prodrug that induces DNA damage within hypoxic regions of tumors, potentially providing antineoplastic activity (PMID: 18666379, PMID: 32543771).

CAS Registry Number 27314-97-2


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Pembrolizumab + Tirapazamine Pembrolizumab Tirapazamine 0 1
Tirapazamine Tirapazamine 0 2

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