Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name GLA-SE
Trade Name
Synonyms G100|TLR-4 agonist G100|glucopyranosyl lipid A stable emulsion
Drug Descriptions

GLA-SE is an immune adjuvant that binds to and activates toll-like receptor 4 (TLR4), leading to activation of innate immunity (PMID: 22147791).

DrugClasses TLR4 Agonist 2
CAS Registry Number 1246298-63-4
NCIT ID C113649

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + GLA-SE + Pembrolizumab Cyclophosphamide GLA-SE Pembrolizumab 0 1
GLA-SE GLA-SE 0 1
GLA-SE + MART-1 antigen GLA-SE MART-1 antigen 0 1
GLA-SE + Pembrolizumab GLA-SE Pembrolizumab 0 1


Additional content available in CKB BOOST