Drug Detail


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Drug Name GLA-SE
Trade Name
Synonyms G100|TLR-4 agonist G100|glucopyranosyl lipid A stable emulsion
Drug Descriptions

GLA-SE is an immune adjuvant that binds to and activates toll-like receptor 4 (TLR4), leading to activation of innate immunity (PMID: 22147791).

DrugClasses TLR4 Agonist 2
CAS Registry Number 1246298-63-4
NCIT ID C113649


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + GLA-SE + Pembrolizumab Cyclophosphamide GLA-SE Pembrolizumab 0 1
GLA-SE + MART-1 antigen GLA-SE MART-1 antigen 0 1
GLA-SE + Pembrolizumab GLA-SE Pembrolizumab 0 1

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