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PLX7904 is a small molecule inhibitor that preferentially inhibits BRAF V600E over wild-type BRAF and CRAF without activating MAPK signaling, therefore leads to growth inhibition in tumor cells (PMID: 26466569, PMID: 28659148).
|DrugClasses||BRAF Inhibitor 20|
|CAS Registry Number||1393465-84-3|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|